Your kidneys also help control your blood pressure by sensing the blood pressure and secreting a hormone, called renin, into your bloodstream. The amount of renin secreted by your kidneys can help regulate your blood pressure if it is too high or too low. When your kidney blood vessels narrow or have a clot, your kidney is less able to do its work. Your physician may diagnose you with renal artery stenosis or renal vein thrombosis.
You may not notice any symptoms. Renovascular conditions develop slowly and worsen over time. If you have high blood pressure, the first sign that you may have renal artery stenosis is that your high blood pressure may become worse or the medications that you take to control your high blood pressure may not be as effective. Other signs of renal artery stenosis are a whooshing sound in your abdomen that your physician hears through a stethoscope, decreased kidney function, congestive heart failure or, eventually, a small shrunken kidney.
When renal vein thrombosis occurs, a clot in your vein may break free or block the flow in a healthy blood vessel.
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In renal artery stenosis, the artery carrying blood into a kidney has narrowed, as opposed to renal artery occlusion in which one or both of the renal arteries has become blocked. In renal vein thrombosis, the renal veins are blocked. Renal atheroembolism affects the renal arterioles–the smallest segment of the blood vessel which feeds the capillaries. Arterial nephrosclerosis results from inflammation and cell death occurring in the renal arteries. And scleroderma renal disease is a complication of a skin disorder which has caused lesions in the arteries.
Because the condition generally progresses over time, there are no early warning signs; so the disease might not be diagnosed until after damage has been done. This can be especially true if the blockage is only affecting one kidney–as the other kidney is capable of doing the work for two.
In renal artery occlusion and renal vein thrombosis, when both kidneys are blocked suddenly, a person might experience back or side pain, blood in the urine, fever, nausea or vomiting. In the case of complete blockage, there might be no urine at all. With renal atheroembolism, there is a chance of having embolisms elsewhere in the body–such as in the retina.
Diagnosis begins with a physical exam and patient interview with questions about general health, medical history, and symptoms.
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